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BNFC November 2025 Update

This update contains 31 significant changes, 2 new monographs, and 1 deleted monograph

Significant Changes:

  • Antibacterials, use for prophylaxis: updated guidance for Haemophilus influenzae type b infection: prevention of secondary disease.
  • Azithromycin: new indication and dose for prevention of secondary cases of Haemophilus influenzae type b disease.
  • Bee venom extract: name change to bee venom extracts.
  • Ciprofloxacin: new indication and dose for prevention of secondary cases of Haemophilus influenzae type b disease.
  • COVID-19 vaccine: monograph updated to reflect current guidance.
  • COVID-19 vaccines: updated guidance for immunisation.
  • Diphtheria vaccine: updated guidance for immunisation.
  • Factor VIIa (recombinant): name change to factor VIIa.
  • Factor XIII A-subunit (recombinant): name change to factor XIII A-subunit.
  • Fibrinogen, dried: name change to fibrinogen.
  • Grass pollen extract: name change to grass pollen extracts.
  • Haemophilus influenzae type b conjugate vaccine: updated guidance for immunisation.
  • Heparin (unfractionated): name change to heparin.
  • Hepatitis B vaccine: updated guidance for immunisation.
  • House dust mite extract: name change to house-dust mite extracts.
  • Hydroxyethylcellulose: name change to hyetellose.
  • Immunisation schedule: updated guidance.
  • Liraglutide: monograph updated to incorporate new preparations.
  • Measles, Mumps and Rubella vaccine: updated guidance for immunisation.
  • Meningococcal vaccines: updated guidance for immunisation.
  • Paracetamol: reminder that taking paracetamol during pregnancy remains safe [MHRA/CHM advice].
  • Paraffin, yellow, soft: name change to yellow soft paraffin.
  • Pertussis vaccine: updated guidance for immunisation.
  • Pneumococcal vaccine: updated guidance for immunisation.
  • Poliomyelitis vaccine: updated guidance for immunisation.
  • Protein C concentrate: name change to protein C.
  • Silver sulfadiazine: name change to sulfadiazine silver.
  • Tetanus vaccine: updated guidance for immunisation.
  • Tree pollen extract: name change to tree pollen extracts.
  • Vaccination, general principles: updated guidance for vaccines and asplenia, splenic dysfunction, or complement disorders.
  • Wasp venom extract: name change to wasp venom extracts.

New Monographs:

  • Tzield® [teplizumab].
  • Vimkunya® [chikungunya vaccine (inactivated)].

 

Deleted Monographs: Victoza® [liraglutide].

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